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              當前位置:首頁技術(shù)文章Wnt receptor抗原,Wnt信號受體蛋白/Frizzled homolog 1抗原

              Wnt receptor抗原,Wnt信號受體蛋白/Frizzled homolog 1抗原

              更新時間:2024-11-12點擊次數(shù):71

              Recombinant human Wnt receptor   

              Frizzled-1; Frizzled homolog 1 (Drosophila); Fz1; hFz1; Fz-1; FZD1; FzE1; Wnt receptor; FZD1_HUMAN.   

              濃度:1mg/ ml

              來源:Recombinant Human

              純度:95% SDS-PAGE

              表達系統(tǒng):Escherichia coli

              標簽:His tag   

              蛋白長度:Full length protein

              內(nèi)毒素水平:<1.000 Eu/µg

              純化方法:HPLC

              應用:SDS-PAGEWestern blotELISA

              Biological activity,immunology research

              保存:-20

              保質(zhì)期:1

              Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK3 kinase, nuclear accumulation of beta catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt mediated inactivation of GSK3 kinase. Both pathways seem to involve interactions with G proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.



              產(chǎn)品名稱:Rabbit Anti-Wnt receptor antibody

              Rabbit Anti-Wnt receptor 

              別名:Frizzled-1; Frizzled homolog 1 (Drosophila); Fz1; hFz1; Fz-1; FZD1; FzE1; Wnt receptor; FZD1_HUMAN.                

              來源:Rabbit

              克隆類型:Polyclonal

              濃度:1mg/ml

              亞型:IgG

              反應:Human,Rat (predicted: Mouse,Pig,Cow,Chicken,Dog,Horse)

              應用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

                     IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

              免疫原:KLH conjugated synthetic peptide derived from human Wnt receptor

              保存:-20
              保質(zhì)期:1

               

               

              產(chǎn)品名稱:Anti-Wnt receptor antibody

              Mouse Anti-Wnt receptor

              別名:Frizzled-1; Frizzled homolog 1 (Drosophila); Fz1; hFz1; Fz-1; FZD1; FzE1; Wnt receptor; FZD1_HUMAN.                  

              來源:Mouse

              克隆類型:Monoclonal

              濃度:1mg/ml

              亞型:IgG

              反應:Human

              應用:WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

                     IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

              反應:  Human

              免疫原:KLH conjugated synthetic peptide derived from human Wnt receptor

              保存:-20
              保質(zhì)期:1

              Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK3 kinase, nuclear accumulation of beta catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt mediated inactivation of GSK3 kinase. Both pathways seem to involve interactions with G proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.


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